Application of vacuum homogenizer technology

In the whole production process of emulsion drugs such as ointment and cream, it must be controlled according to strict product hygiene or sterility standards. All raw materials must be homogenized, heated, cooled, sterilized and filled in a quantitative manner under controlled, safe and repeatable conditions. The production system must include CIP, SIP and other devices; In addition, in order to record and track, the whole production process is automated and meets the requirements of good automated manufacturing practice (gamp) .

The traditional method of batch preparation of emulsion is to use stainless steel stirring tank and disperser. In the process of mixing and dispersing, it is necessary to add active ingredients under laminar flow, which involves a large number of manual process steps. Moreover, because the stainless steel mixing tank is suitable for products with simple mixing needs, such as liquid washing products, its mixing efficiency is limited, and the preparation of cream, ointment, gel and other pharmaceutical products with higher dispersion and homogeneous emulsification needs is very time-consuming. Nowadays, the emulsification system launched by Wuxi Yikai, a professional emulsifying machine manufacturer, can concentrate all process steps in one tank system, and add vacuum function to the production process, which can more effectively realize mixing and homogenization. In addition, Eckart also provides customized services for each customer, so that the system can better save investment cost, floor space and cleaning time, and simplify the whole production process.

The vacuum emulsifying machine is the first selected system that has been verified for the production of cream, lotion, gel, ointment and other types of dispersive dosage forms. Eckart machines and related automation concepts can meet the special requirements of all aspects in the production process of parenteral, pulmonary, oral and percutaneous dosage forms, and provide an ideal platform for accurately processing products with a wide range of viscosities.